麻醉药物对肿瘤患者免疫功能的影响

doi:10.12337/zgkqjxjyzz.2023.06.010

中国口腔医学继续教育杂志 ›› 2023, Vol. 26 ›› Issue (6): 474-478.DOI: 10.12337/zgkqjxjyzz.2023.06.010

麻醉药物对肿瘤患者免疫功能的影响

黄丽丽^1,2, 张铁军^1,2,*

¹口颌系统重建与再生全国重点实验室,口腔生物医学教育部重点实验室,口腔医学湖北省重点实验室,武汉大学口腔医(学)院;
²武汉大学口腔医院麻醉科

出版日期:2023-11-30 发布日期:2024-03-13
通讯作者: ^*张铁军,联系方式：027-87686242,电子邮箱：ztj@whu.edu.cn,通讯地址：湖北省武汉市洪山区珞喻路237号,430079
基金资助:
湖北省自然科学基金面上项目（项目编号：2022CFB065）

Effects of Anesthetics on Immune Function in Patients with Tumor

Lili Huang^1,2, Tiejun Zhang^1,2,*

¹The State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University;
²Department of Anesthesiology, School and Hospital of Stomatology, Wuhan University

Online:2023-11-30 Published:2024-03-13
Contact: ^*Tiejun Zhang. Tel: 027-87686242. Email: ztj@whu.edu.cn. Address: No.237, Luoyu Road, Hongshan District, Wuhan 430079, Hubei Province, P.R.China.
Supported by:
Hubei Natural Science Foundation(No:2022CFB065)

摘要/Abstract

摘要： 人体免疫系统包括先天性免疫和获得性免疫两大部分,为宿主抵抗病原体和肿瘤侵袭发挥重要作用。大量研究试图了解麻醉药物对免疫功能的影响。本文综述最常见的麻醉药物对肿瘤患者先天性免疫和获得性免疫的影响,包括吸入性麻醉药、静脉麻醉药、阿片类药物以及局部麻醉药。每一种麻醉药物对免疫系统有独特的影响,对于肿瘤患者需制定适合患者的特异性治疗策略,以优化短期和长期的手术疗效。

关键词: 麻醉药物, 免疫功能, 肿瘤患者, 肿瘤转移, 手术

Abstract: The immune system is classically divided into innate and adaptive components, which play an important role in the host’s resistance to pathogens and tumor invasion. A large number of studies have attempted to understand the effects of anesthetics on immune function. The most commonly used anesthetic agents were chosen in this review including volatile agents, intravenous agents, opioids, and local anesthetics. Each has unique effect on the immune system. Specific treatment strategies need to be developed to improve short and long term surgical outcomes for patients with malignant tumors.

Key words: anesthetics, immune, tumor patients, tumor metastasis, surgery

黄丽丽, 张铁军. 麻醉药物对肿瘤患者免疫功能的影响[J]. 中国口腔医学继续教育杂志, 2023, 26(6): 474-478.

Lili Huang, Tiejun Zhang. Effects of Anesthetics on Immune Function in Patients with Tumor[J]. Chinese Journal of Stomatological Continuing Education, 2023, 26(6): 474-478.

参考文献

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麻醉药物对肿瘤患者免疫功能的影响

Effects of Anesthetics on Immune Function in Patients with Tumor

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