Abstract: Objective: This article reported a case of multidisciplinary combined treatment of epulis due to dens invaginatus. Diagnosis and treatment: After clear diagnosis and informed consent, the patient underwent multidisciplinary treatment, including periodontal initial therapy and root canal treatment, followed by epulis excision and apical surgical resection; after inflammation control, connective tissue grafting was carried out for gingival soft tissue augmentation and prosthodontic treatment to restore the aesthetics. Results: Two and a half years after epulis resection, no recurrence of epulis; no percussion pain in the tooth, no sinus tract; no obvious recession of the labial gingiva, no obvious periodontitis, and stable clinical results of the restoration. Conclusions: Dens invaginatus is a rare disease, for the treatment of dens invaginatus, the key lies in early detection, and at the same time combining with the type of invagination, pulpal infection and the degree of periodontal destruction to choose the appropriate treatment programs.

Key words: dens invaginatus, epulis, palatal radicular groove, combined periodontal-endodontic lesions, connective tissue graft