中国口腔医学继续教育杂志 ›› 2026, Vol. 29 ›› Issue (1): 25-34.DOI: 10.12337/zgkqjxjyzz.2026.01.004

• 临床研究 • 上一篇    下一篇

意向性牙再植用于治疗难治性磨牙根尖周炎的回顾性研究

刘畅, 雍颹, 赵晓一, 齐伟, 周维, 朱文昊*   

  1. 北京大学口腔医学院·口腔医院,综合治疗科,国家口腔医学中心,国家口腔疾病临床医学研究中心,口腔生物材料和数字诊疗装备国家工程研究中心
  • 出版日期:2026-01-31 发布日期:2026-01-31
  • 通讯作者: *朱文昊,联系方式:010-82195586,电子邮箱:zhweha@163.com,通讯地址:北京市海淀区中关村南大街22号,100081
  • 基金资助:
    北京大学口腔医院新技术新疗法项目(项目编号:PKUSSNCT-12B06)(意向性牙再植的临床研究)

Retrospective Study of Intentional Tooth Replantation for the Treatment of Refractory Periapical Periodontitis in Molars

Chang Liu, Wei Yong, Xiaoyi Zhao, Wei Qi, Wei Zhou, Wenhao Zhu*   

  1. Department of General Dentistry, Peking University School and Hospital of Stomatology & National Center for Stomatology & National Clinical Research Center for Oral Diseases & National Engineering Research Center of Oral Biomaterials and Digital Medical Devices, Beijing, P.R. China
  • Online:2026-01-31 Published:2026-01-31
  • Contact: Wenhao Zhu. Tel: 010-82195586. Email: zhweha@163.com. Address: No.22, Zhongguancun South Avenue, Haidian District, Beijing 100081, P.R. China.
  • Supported by:
    Supported by:Peking University Hospital of Stomatology 2012 Annual Clinical New Technologies and New Therapies Program(No.PKUSSNCT-12B06)

摘要: 目的: 回顾性分析“意向性牙再植”治疗难治性磨牙根尖周炎的临床疗效,为该类患牙的保存治疗提供依据。方法: 选取2012-2024年于北京大学口腔医院综合科接受“意向性牙再植”治疗的磨牙病例。经微创拔出、显微镜下评估根尖情况,行截除根尖3mm、根尖倒预备、根尖倒充填,植回拔牙窝并固定。术后定期开展临床随访并拍摄X线片,评估根尖周病变愈合情况及牙周膜愈合形式,统计术后12个月牙齿存留率及成功率。结果: 共纳入18例病例,随访时间12~77个月。术后12个月牙齿存留率为 88.9%(16/18),成功率61.1%(11/18) (无症状且X 线片示根尖周病变完全愈合),27.8%(5/18)病例无临床症状且病变缩小,牙周愈合方式均为牙周膜愈合,未发生根骨固连。2例患牙因根分叉穿孔、严重根外感染无法控制而拔除。结论: 基于现代显微根尖手术理念,严格规范操作流程的意向性牙再植术,可作为牙髓根尖周病变患牙保存治疗的有效补充手段。

关键词: 意向性牙再植, 根尖周炎, 显微根尖手术, 存留率, 磨牙

Abstract: Objective: To retrospectively analyze the clinical efficacy of intentional tooth replantation in the treatment of refractory periapical periodontitis of molars, and to provide evidence for the preservation therapy of such affected teeth. Methods: Molar cases that underwent intentional tooth replantation in the General Dentistry Department of Peking University School and Hospital of Stomatology between 2012 and 2024 were selected. The procedure involved minimally traumatic extraction, microscopic assessment of the apical region, resection of the apical 3 mm, retrograde cavity preparation, and retrofilling, followed by replantation into the original socket and stabilization. Regular clinical follow-ups and X-ray examinations were performed postoperatively to evaluate the healing of periapical lesions and the pattern of periodontal ligament healing, and the tooth survival rate at 12 months after surgery was calculated. Results: A total of 18 cases were included, with a follow-up period ranging from 12 to 77 months. The tooth survival rate at 12 months postoperatively was 88.9%(16/18). Success rate was 61.1%(11/18) (asymptomatic with complete periapical lesion healing shown radiographically), while 27.8%(5/18) of cases exhibited no clinical symptoms with lesion size reduction. All periodontal healing patterns were periodontal ligament healing without ankylosis. 2 affected teeth were extracted due to furcation perforation or severe external root infection. Conclusions: Based on the concept of modern microscopic periapical surgery, intentional tooth replantation with strictly standardized operational procedures can serve as an effective supplementary method for the preservation therapy of teeth with periapical lesions.

Key words: intentional replantation, periapical periodontitis, endodontic microsurgery, survival rate, molar