光生物调节作用对颅颌面骨修复的影响

doi:10.12337/zgkqjxjyzz.2023.04.001

中国口腔医学继续教育杂志 ›› 2023, Vol. 26 ›› Issue (4): 233-239.DOI: 10.12337/zgkqjxjyzz.2023.04.001

• 综述 • 下一篇

光生物调节作用对颅颌面骨修复的影响

彭金枫^1,2,3, 唐清明^1,2,3, 陈莉莉^1,2,3,*

¹华中科技大学同济医学院附属协和医院口腔医学中心;
²华中科技大学同济医学院口腔医学院;
³口腔颌面发育与再生湖北省重点实验室

出版日期:2023-07-31 发布日期:2023-11-29
通讯作者: *陈莉莉,联系方式：027-85726949,电子邮箱：chenlili1030@hust.edu.cn,通讯地址：湖北省武汉市江汉区解放大道1277号,430022
基金资助:
国家重点研发计划（项目编号：2021YFC2400400）

Effects of Photobiomodulation on Craniomaxillofacial Bone Repair

Jinfeng Peng^1,2,3, Qingming Tang^1,2,3, Lili Chen^1,2,3,*

¹Department of Stomatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, P.R. China;
²School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, P.R. China;
³Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration, Wuhan, Hubei Province, P.R. China

Online:2023-07-31 Published:2023-11-29
Contact: Lili Chen. Tel: 027-85726949. Email: chenlili1030@hust.edu.cn. Address: No.1277 Jiefang Avenue, Jianghan District, Wuhan 430022, Hubei Province, P.R. China
Supported by:
National Key Research and Development Program of China (No.2021YFC2400400)

摘要/Abstract

摘要： 目前颅颌面骨缺损相关疾病面临修复速率较慢、骨再生能力有限等问题,常导致缺损区域愈合延迟甚至不愈合,严重影响患者生活质量,寻找更为高效的颅颌面骨修复策略已成为该领域重点研究方向。光生物调节作用是指利用不同光源引发对机体的光物理和光化学调节作用,具有非侵入性、操作简单、时空精度高等优点,为加速颅颌面骨修复提供一种有前景的方式。本文系统总结光生物调节作用调控颅颌面骨修复的有效参数,阐述光生物调节作用对颅颌面骨修复的作用机制,并对目前光生物调节装置在临床的转化应用进行总结展望,为实现高效、安全的颅颌面骨修复策略提供参考。

关键词: 光生物调节作用, 骨缺损, 颅颌面骨修复, 生物学效应, 细胞分化

Abstract: Craniomaxillofacial bone defects are with problems such as slow repair rate and limited bone regeneration ability, which often lead to delayed or even non-healing of the defect area, seriously affecting the quality of life of patients. Finding more efficient craniomaxillofacial bone repair strategies has become a key research direction in the field. Photobiomodulation refers to the method of using different light sources to produce beneficial therapeutic effects, which has the advantages of non-invasive, simple operation and high spatial and temporal accuracy, and provides a promising way to accelerate cranio-maxillofacial bone repair. In this review, we systematically summarized the effective parameters of photobiomodulation on craniomaxillofacial bone repair, elaborated the mechanisms of photobiomodulation on craniomaxillofacial bone repair, and summarized the prospects of the current clinical transformation application of photobiomodulation devices, so as to provide reference for realizing efficient and safe craniomaxillofacial bone repair strategies.

Key words: photobiomodulation, bone defects, craniomaxillofacial bone repair, biological effects, cell differentiation

彭金枫, 唐清明, 陈莉莉. 光生物调节作用对颅颌面骨修复的影响[J]. 中国口腔医学继续教育杂志, 2023, 26(4): 233-239.

Jinfeng Peng, Qingming Tang, Lili Chen. Effects of Photobiomodulation on Craniomaxillofacial Bone Repair[J]. Chinese Journal of Stomatological Continuing Education, 2023, 26(4): 233-239.

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光生物调节作用对颅颌面骨修复的影响

Effects of Photobiomodulation on Craniomaxillofacial Bone Repair

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