Effects of Photobiomodulation on Craniomaxillofacial Bone Repair

doi:10.12337/zgkqjxjyzz.2023.04.001

Chinese Journal of Stomatological Continuing Education ›› 2023, Vol. 26 ›› Issue (4): 233-239.DOI: 10.12337/zgkqjxjyzz.2023.04.001

Effects of Photobiomodulation on Craniomaxillofacial Bone Repair

Jinfeng Peng^1,2,3, Qingming Tang^1,2,3, Lili Chen^1,2,3,*

¹Department of Stomatology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, P.R. China;
²School of Stomatology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, P.R. China;
³Hubei Province Key Laboratory of Oral and Maxillofacial Development and Regeneration, Wuhan, Hubei Province, P.R. China

Online:2023-07-31 Published:2023-11-29
Contact: Lili Chen. Tel: 027-85726949. Email: chenlili1030@hust.edu.cn. Address: No.1277 Jiefang Avenue, Jianghan District, Wuhan 430022, Hubei Province, P.R. China
Supported by:
National Key Research and Development Program of China (No.2021YFC2400400)

Abstract

Abstract: Craniomaxillofacial bone defects are with problems such as slow repair rate and limited bone regeneration ability, which often lead to delayed or even non-healing of the defect area, seriously affecting the quality of life of patients. Finding more efficient craniomaxillofacial bone repair strategies has become a key research direction in the field. Photobiomodulation refers to the method of using different light sources to produce beneficial therapeutic effects, which has the advantages of non-invasive, simple operation and high spatial and temporal accuracy, and provides a promising way to accelerate cranio-maxillofacial bone repair. In this review, we systematically summarized the effective parameters of photobiomodulation on craniomaxillofacial bone repair, elaborated the mechanisms of photobiomodulation on craniomaxillofacial bone repair, and summarized the prospects of the current clinical transformation application of photobiomodulation devices, so as to provide reference for realizing efficient and safe craniomaxillofacial bone repair strategies.

Key words: photobiomodulation, bone defects, craniomaxillofacial bone repair, biological effects, cell differentiation

Jinfeng Peng, Qingming Tang, Lili Chen. Effects of Photobiomodulation on Craniomaxillofacial Bone Repair[J]. Chinese Journal of Stomatological Continuing Education, 2023, 26(4): 233-239.

References

[1] Schuett DJ, Hake ME, Mauffrey C, et al.Current Treatment Strategies for Patella Fractures[J]. Orthopedics. 2015; 38(6):377-384.
[2] Yong EL, Logan S.Menopausal osteoporosis: screening, prevention and treatment[J]. Singapore Med J. 2021; 62(4):159-166.
[3] Iglesias L, Yeh JK, Castro-Magana M, et al.Effects of growth hormone on bone modeling and remodeling in hypophysectomized young female rats: a bone histomorphometric study[J]. J Bone Miner Metab. 2011; 29(2):159-167.
[4] Telatar BC, Gungor AY.Effectiveness of vibrational forces on orthodontic treatment: A randomized, controlled clinical trial[J]. J Orofac Orthop. 2021; 82(5):288-294.
[5] Miles P, Fisher E, Pandis N.Assessment of the rate of premolar extraction space closure in the maxillary arch with the AcceleDent Aura appliance vs no appliance in adolescents: A single-blind randomized clinical trial[J]. Am J Orthod Dentofacial Orthop. 2018; 153(1):8-14.
[6] Almpani K, Kantarci A.Nonsurgical Methods for the Acceleration of the Orthodontic Tooth Movement[J]. Front Oral Biol. 2016; 18:80-91.
[7] Anders JJ, Lanzafame RJ, Arany PR.Low-level light/laser therapy versus photobiomodulation therapy[J]. Photomed Laser Surg. 2015; 33(4):183-184.
[8] Adelman MR, Tsai LJ, Tangchitnob EP, et al.Laser technology and applications in gynaecology[J]. J Obstet Gynaecol. 2013; 33(3):225-231.
[9] Chen Z, Huang S, Liu M.The review of the light parameters and mechanisms of Photobiomodulation on melanoma cells[J]. Photodermatol Photoimmunol Photomed. 2022; 38(1):3-11.
[10] Mester A, Mester A.The History of Photobiomodulation: Endre Mester (1903-1984)[J]. Photomed Laser Surg. 2017; 35(8):393-394.
[11] Schultz RJ, Krishnamurthy S, Thelmo W, et al.Effects of varying intensities of laser energy on articular cartilage: a preliminary study[J]. Lasers Surg Med. 1985; 5(6):577-588.
[12] Trelles MA, Mayayo E.Bone fracture consolidates faster with low-power laser[J]. Lasers Surg Med. 1987; 7(1):36-45.
[13] Guzzardella GA, Fini M, Torricelli P, et al.Laser stimulation on bone defect healing: an in vitro study[J]. Lasers Med Sci. 2002; 17(3):216-220.
[14] Lin JT.Progress of medical lasers: Fundamentals and Applications[J]. Med Devices Diagn Eng, 2016; 2(1):36-41.
[15] Bölükbaşı Ateş G, Ak A, Garipcan B, et al.Photobiomodulation effects on osteogenic differentiation of adipose-derived stem cells[J]. Cytotechnology. 2020; 72(2):247-258.
[16] Peng J, Zhao J, Tang Q, et al.Low intensity near-infrared light promotes bone regeneration via circadian clock protein cryptochrome 1[J]. Int J Oral Sci. 2022; 14(1):53.
[17] Finlayson L, Barnard IRM, McMillan L, et al. Depth Penetration of Light into Skin as a Function of Wavelength from 200 to 1000 nm[J]. Photochem Photobiol. 2022; 98(4):974-981.
[18] Zein R, Selting W, Hamblin MR.Review of light parameters and photobiomodulation efficacy: dive into complexity[J]. J Biomed Opt. 2018; 23(12):1-17.
[19] Lima AMCT, da Silva Sergio LP, de Souza da Fonseca A. Photobiomodulation via multiple-wavelength radiations[J]. Lasers Med Sci. 2020; 35(2):307-316.
[20] Obodovskiy I.6-Radiation and Chemical Hormesis[M]. Fundamentals of radiation and chemical safety. Amsterdam: Elsevier, 2015:181-213.
[21] Calabrese EJ.The emergence of the dose-response concept in biology and medicine[J]. Int J Mol Sci. 2016; 17(12):2034.
[22] Flores Luna GL, de Andrade ALM, Brassolatti P, et al. Biphasic Dose/Response of photobiomodulation therapy on culture of human fibroblasts[J]. Photobiomodul Photomed Laser Surg. 2020; 38(7):413-418.
[23] Bouvet-Gerbettaz S, Merigo E, Rocca JP, et al.Effects of low-level laser therapy on proliferation and differentiation of murine bone marrow cells into osteoblasts and osteoclasts[J]. Lasers Surg Med. 2009; 41(4):291-297.
[24] Deana AM, de Souza AM, Teixeira VP, et al. The impact of photobiomodulation on osteoblast-like cell: a review[J]. Lasers Med Sci. 2018; 33(5):1147-1158.
[25] Coskun ME, Coskun KA, Tutar Y.Determination of Optimum Operation Parameters for Low-Intensity Pulsed Ultrasound and Low-Level Laser Based Treatment to Induce Proliferation of Osteoblast and Fibroblast Cells[J]. Photomed Laser Surg. 2018; 36(5):246-252.
[26] Borzabadi-Farahani A.Effect of low-level laser irradiation on proliferation of human dental mesenchymal stem cells; a systemic review[J]. J Photochem Photobiol B. 2016; 162:577-582.
[27] Zecha JA, Raber-Durlacher JE, Nair RG, et al.Low level laser therapy/photobiomodulation in the management of side effects of chemoradiation therapy in head and neck cancer: part 1: mechanisms of action, dosimetric, and safety considerations[J]. Support Care Cancer. 2016; 24(6):2781-2792.
[28] Wu X, Moges H, Detaboada L, et al.Comparison of the effects of pulsed and continuous wave light on axonal regeneration in a rat model of spinal cord injury[J]. Lasers Med Sci. 2012; 27(2):525-528.
[29] Barbora A, Bohar O, Sivan AA, et al.Higher pulse frequency of near-infrared laser irradiation increases penetration depth for novel biomedical applications[J]. PLoS One. 2021; 16(1):e0245350.
[30] Joensen J, Ovsthus K, Reed RK, et al.Skin penetration time-profiles for continuous 810 nm and Superpulsed 904 nm lasers in a rat model[J]. Photomed Laser Surg. 2012; 30(12):688-694.
[31] Hashmi JT, Huang YY, Sharma SK, et al.Effect of pulsing in low-level light therapy[J]. Lasers Surg Med. 2010; 42(6):450-466.
[32] Hanna R, Agas D, Benedicenti S, et al.A Comparative Study Between the Effectiveness of 980 nm Photobiomodulation Delivered by Hand-Piece With Gaussian vs. Flat-Top Profiles on Osteoblasts Maturation[J]. Front Endocrinol (Lausanne). 2019; 10:92.
[33] Agas D, Hanna R, Benedicenti S, et al.Photobiomodulation by Near-Infrared 980-nm Wavelengths Regulates Pre-Osteoblast Proliferation and Viability through the PI3K/Akt/Bcl-2 Pathway[J]. Int J Mol Sci. 2021; 22(14):7586.
[34] Moncada S, Erusalimsky JD.Does nitric oxide modulate mitochondrial energy generation and apoptosis?[J]. Nat Rev Mol Cell Biol. 2002; 3(3):214-220.
[35] Brookes PS, Levonen AL, Shiva S, et al.Mitochondria: regulators of signal transduction by reactive oxygen and nitrogen species[J]. Free Radic Biol Med. 2002; 33(6):755-764.
[36] Karu T.Primary and secondary mechanisms of action of visible to near-IR radiation on cells[J]. J Photochem Photobiol B. 1999; 49(1):1-17.
[37] Avci P, Nyame TT, Gupta GK, et al.Low-level laser therapy for fat layer reduction: a comprehensive review[J]. Lasers Surg Med. 2013; 45(6):349-357.
[38] Mikami R, Mizutani K, Aoki A, et al.Low-level ultrahigh-frequency and ultrashort-pulse blue laser irradiation enhances osteoblast extracellular calcification by upregulating proliferation and differentiation via transient receptor potential vanilloid 1[J]. Lasers Surg Med. 2018; 50(4):340-352.
[39] Serrage H, Heiskanen V, Palin WM, et al.Under the spotlight: mechanisms of photobiomodulation concentrating on blue and green light[J]. Photochem Photobiol Sci. 2019; 18(8):1877-1909.
[40] Wang Y, Huang YY, Wang Y, et al.Photobiomodulation (blue and green light) encourages osteoblastic-differentiation of human adipose-derived stem cells: role of intracellular calcium and light-gated ion channels[J]. Sci Rep. 2016; 6:33719.
[41] Wang Y, Huang YY, Wang Y, et al.Red (660nm) or near-infrared (810nm) photobiomodulation stimulates, while blue (415nm), green(540nm) light inhibits proliferation in human adipose-derived stem cells[J]. Sci Rep. 2017; 7(1):7781.
[42] Notomi T, Kuno M, Hiyama A, et al.Membrane depolarization regulates intracellular RANKL transport in non-excitable osteoblasts[J]. Bone. 2015; 81:306-314.
[43] Kim HJ, Son ED, Jung JY, et al.Violet light down-regulates the expression of specific differentiation markers through Rhodopsin in normal human epidermal keratinocytes[J]. PLoS One. 2013; 8(9):e73678.
[44] Cronin MA, Lieu MH, Tsunoda S.Two stages of light-dependent TRPL-channel translocation in Drosophila photoreceptors[J]. J Cell Sci. 2006; 119(Pt 14):2935-2944.
[45] Sies H, Jones DP.Reactive oxygen species (ROS) as pleiotropic physiological signalling agents[J]. Nat Rev Mol Cell Biol. 2020; 21(7):363-383.
[46] Boyce BF, Xing L.Functions of RANKL/RANK/OPG in bone modeling and remodeling[J]. Arch Biochem Biophys. 2008; 473(2):139-146.
[47] Cifter M, Celikel ADG, Cifter ED, et al.Comparison of the efficiency of alveolar decortication and low level laser therapy on orthodontic tooth movement and alveolar metabolism in rats[J]. J Dent Sci. 2019; 14(4):401-407.
[48] Dandajena TC, Ihnat MA, Disch B, et al.Hypoxia triggers a HIF-mediated differentiation of peripheral blood mononuclear cells into osteoclasts[J]. Orthod Craniofac Res. 2012; 15(1):1-9.
[49] Bai J, Li L, Kou N, et al.Low level laser therapy promotes bone regeneration by coupling angiogenesis and osteogenesis[J]. Stem Cell Res Ther. 2021; 12(1):432.
[50] Chen W, Wu P, Yu F, et al.HIF-1α Regulates Bone Homeostasis and Angiogenesis, Participating in the Occurrence of Bone Metabolic Diseases[J]. Cells. 2022; 11(22):3552.
[51] Lee G, Kim B, Ko Y, et al.Regulation of RANKL-Induced Osteoclastogenesis by 635-nm Light-Emitting Diode Irradiation Via HSP27 in Bone Marrow-Derived Macrophages[J]. Photomed Laser Surg. 2017; 35(2):78-86.
[52] Jettar V, Napimoga MH, Freitas F, et al.Effects of Photobiomodulation on SOFAT, A T-cell-derived Cytokine, May Explain Accelerated Orthodontic Tooth Movement[J]. Photochem Photobiol. 2018; 94(3):604-610.
[53] Kular J, Tickner J, Chim SM, et al.An overview of the regulation of bone remodelling at the cellular level[J]. Clin Biochem. 2012; 45(12):863-873.
[54] Bellido T.Osteocyte-driven bone remodeling[J]. Calcif Tissue Int. 2014; 94(1):25-34.
[55] Wan Z, Zhang P, Lv L, et al.NIR light-assisted phototherapies for bone-related diseases and bone tissue regeneration: A systematic review[J]. Theranostics. 2020; 10(25):11837-11861.
[56] Yang J, Fu Q, Jiang H, et al.Progress of phototherapy for osteosarcoma and application prospect of blue light photobiomodulation therapy[J]. Front Oncol. 2022; 12:1022973.
[57] Matos DS, Palma-Dibb RG, de Oliveira Santos C, et al. Evaluation of photobiomodulation therapy to accelerate bone formation in the mid palatal suture after rapid palatal expansion: a randomized clinical trial[J]. Lasers Med Sci. 2021; 36(5):1039-1046.
[58] Pereira DA, Mendes PGJ, de Souza Santos S, et al. Effect of the association of infra-red and red wavelength photobiomodulation therapy on the healing of post-extraction sockets of third lower molars: a split-mouth randomized clinical trial[J]. Lasers Med Sci. 2022; 37(5):2479-2487.
[59] Cepera F, Torres FC, Scanavini MA, et al.Effect of a low-level laser on bone regeneration after rapid maxillary expansion[J]. Am J Orthod Dentofacial Orthop. 2012; 141(4):444-450.
[60] Ferreira FN, Gondim JO, Neto JJ, et al.Effects of low-level laser therapy on bone regeneration of the midpalatal suture after rapid maxillary expansion[J]. Lasers Med Sci. 2016; 31(5):907-913.
[61] Impellizzeri A, Horodynski M, Fusco R, et al.Photobiomodulation Therapy on Orthodontic Movement: Analysis of Preliminary Studies with a New Protocol[J]. Int J Environ Res Public Health. 2020; 17(10):3547.
[62] Monea A, Beresescu G, Boeriu S, et al.Bone healing after low-level laser application in extraction sockets grafted with allograft material and covered with a resorbable collagen dressing: a pilot histological evaluation[J]. BMC Oral Health. 2015; 15:134.
[63] Rosero KAV, Sampaio RMF, Deboni MCZ, et al.Photobiomodulation as an adjunctive therapy for alveolar socket preservation: a preliminary study in humans[J]. Lasers Med Sci. 2020; 35(8):1711-1720.
[64] Saucedo CL, Courtois EC, Wade ZS, et al.Transcranial laser stimulation: Mitochondrial and cerebrovascular effects in younger and older healthy adults[J]. Brain Stimul. 2021; 14(2):440-449.
[65] Behrangi E, Roohaninasab M, Sadeghzadeh-Bazargan A, et al.A systematic review on the treatment of pediatric severe alopecia areata by topical immunotherapy or Anthralin (contact sensitization) or low-level light/laser therapy (LLLT): focus on efficacy, safety, treatment duration, recurrence, and follow-up based on clinical studies[J]. J Cosmet Dermatol. 2022; 21(7):2727-2741.
[66] Magri AMP, Parisi JR, de Andrade ALM, et al. Bone substitutes and photobiomodulation in bone regeneration: A systematic review in animal experimental studies[J]. J Biomed Mater Res A. 2021; 109(9):1765-1775.
[67] Sampurna MTA, Etika R, Utomo MT, et al.An evaluation of phototherapy device performance in a tertiary health facility[J]. Heliyon. 2020; 6(9):e04950.
[68] Phan DT, Bui NT, Vo TH, et al.Development of a LED light therapy device with power density control using a Fuzzy logic controller[J]. Med Eng Phys. 2020; 86:71-77.
[69] Yoon JS, Ku WY, Lee JH, et al.Low-level light therapy using a helmet-type device for the treatment of androgenetic alopecia: A 16-week, multicenter, randomized, double-blind, sham device-controlled trial[J]. Medicine (Baltimore). 2020; 99(29):e21181.
[70] Montealegre A, Charpak N, Parra A, et al.Effectiveness and safety of two phototherapy devices for the humanised management of neonatal jaundice[J]. An Pediatr (Engl Ed). 2020; 92(2):79-87.
[71] Sorbellini E, Rucco M, Rinaldi F.Photodynamic and photobiological effects of light-emitting diode (LED) therapy in dermatological disease: an update[J]. Lasers Med Sci. 2018; 33(7):1431-1439.

Effects of Photobiomodulation on Craniomaxillofacial Bone Repair

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 0

Recommended Articles

Metrics

Comments