Abstract: Objective: To evaluate the impact of the “Internet+” case-based teaching model on enhancing clinical decision-making ability among medical students in the context of medication-related osteonecrosis of the jaw (MRONJ). Methods: A convenience sampling method was adopted. A total of 39 fifth-year undergraduate students majoring in stomatology (Class of 2020) undergoing clinical surgical rotation were assigned to the control group and received traditional teaching. Another cohort of 39 students (Class of 2021) constituted the intervention group and received a reformed teaching model based on Internet+ progressive case learning. Teaching effectiveness was assessed using the self-rating scale of active learning and critical thinking (SSACT), a satisfaction questionnaire, and theoretical/technical examinations. Results: The effectiveness of the “Internet+” case-based teaching reform in MRONJ was comprehensively evaluated across multiple dimensions. The intervention group achieved significantly higher theoretical scores (52.87±3.51vs 44.10±4.81), practical scores (34.00±4.46 vs 30.85±7.28), and total scores (86.95±5.97 vs 74.75±9.08) compared with the control group (all P<0.01). In the study group, there were greater improvements in active learning ability (improvement of 18.94±1.97 vs 14.53±3.09), critical thinking (improvement of 39.54±6.58 vs 33.31±4.75), and total score of clinical thinking ability (improvement of 87.10±9.68 vs 68.54±6.30). Feedback suggested that this model was positively perceived for fostering pre-class preparation, information retrieval, and teamwork. Conclusions: The “Internet+” case-based teaching approach for MRONJ, through the integration of virtual and in-person learning, significantly enhances students’ evidence-based clinical decision-making in complex osteonecrosis cases. Its multidimensional interactive teaching and evaluation framework provides a replicable paradigm for educational reform in oral and maxillofacial surgery.

Key words: medication-related osteonecrosis of the jaw, osteonecrosis, progressive case-based learning, internet, teaching reform