口腔种植科诊疗中的感染控制

doi:10.12337/zgkqjxjyzz.2025.02.002

中国口腔医学继续教育杂志 ›› 2025, Vol. 28 ›› Issue (2): 67-75.DOI: 10.12337/zgkqjxjyzz.2025.02.002

口腔种植科诊疗中的感染控制

俞建宇, 徐淑兰^*

南方医科大学,南方医科大学口腔医院,南方医科大学口腔医院口腔种植中心

发布日期:2025-03-31
通讯作者: ^*徐淑兰,联系方式：020-34304863,电子邮箱：xushulan_672588@smu.edu.cn,通讯地址：广东省广州市海珠区江南大道南366号,510220
基金资助:
广东省临床重点专科和南方医科大学口腔医院临床研究启动计划项目（项目编号：KQIIT2021001）

Infection Control in Oral Implantology

Jianyu Yu, Shulan Xu^*

Southern Medical University, Southern Medical University Stomatological Hospital, Center for Oral Implantology, Southern Medical University Stomatological Hospital, Guangzhou, Guangdong Province, P.R. China.

Published:2025-03-31
Contact: ^*Shulan Xu. Tel: 020-34304863. Email: xushulan_672588@smu.edu.cn. Address: No. 366 Jiangnan Avenue South, Haizhu District, Guangzhou 510220, Guangdong Province, P.R. China.
Supported by:
Guangdong Provincial Key Clinical Specialties and the Southern Medical University Stomatological Hospital Clinical Research Initiation Program (NO. KQIIT2021001)

摘要/Abstract

摘要： 口腔种植学在现代口腔医学中发挥着日益重要的作用,其中感染控制是确保种植手术成功和患者安全的关键环节。随着口腔种植技术的不断发展,术后感染的发生率逐渐受到临床医师和研究者的广泛关注。本文旨在分析口腔种植手术中常见的感染类型及其发生机制,并从术前准备、术中操作、术后护理及医院管理多个角度对感染的防控进行讨论。研究表明,感染控制需贯穿术前、术中和术后全过程：术前患者的全身状况评估和口腔局部准备;术中严格执行无菌操作,优化手术技术;术后患者抗生素的使用,随访管理和健康教育。同时,医院管理体系的完善对感染防控至关重要,包括医院制度制定、手术流程规范、医务人员培训和医院环境监测。此外,本文强调多学科协作在口腔种植科感染控制中的重要性,通过加强各专业间的沟通与合作,可提升整体医疗服务质量,保障患者的安全与满意度。本文希望通过对感染控制措施的深入探讨,为提高口腔种植手术成功率提供理论依据与实践指导。

关键词: 口腔种植, 术后感染, 医院感染, 感染控制, 医院管理

Abstract: Oral implantology plays an increasingly important role in modern dentistry, with infection control being a critical factor to ensure the success of implant surgeries and patient safety. As implant technology continues to advance, postoperative infections have become a major concern for clinicians and researchers.This article analyzes the common types of infections associated with dental implant surgeries and their underlying mechanisms. It further discusses infection prevention and control strategies from multiple perspectives, including preoperative preparation, intraoperative protocols, postoperative care, and hospital management.Research indicates that infection control must be implemented throughout all phases of treatment. Preoperatively, comprehensive assessment of the patient's systemic health and proper preparation of the oral cavity are essential. Intraoperatively, strict adherence to aseptic techniques and optimization of surgical procedures are crucial. Postoperative strategies, such as appropriate use of antibiotics, structured follow-up, and patient health education, also play a key role in minimizing infection risk.Additionally, a well-established hospital management system is indispensable for effective infection control. This includes the development of institutional protocols, standardization of surgical workflows, staff training programs, and continuous environmental monitoring. The article also highlights the importance of multidisciplinary collaboration in infection control within implant dentistry. Enhanced communication and cooperation among various healthcare professionals can significantly improve the overall quality of care and ensure patient safety and satisfaction.Through an in-depth discussion of infection control measures, this study aims to provide a theoretical foundation and practical guidance for improving the success rate of dental implant surgeries.

Key words: dental implants, postoperative infection, nosocomial infection, infection control, hospital management

俞建宇, 徐淑兰. 口腔种植科诊疗中的感染控制[J]. 中国口腔医学继续教育杂志, 2025, 28(2): 67-75.

Jianyu Yu, Shulan Xu. Infection Control in Oral Implantology[J]. Chinese Journal of Stomatological Continuing Education, 2025, 28(2): 67-75.

参考文献

[1] 宫苹, 王佐林, 邸萍, 等. 口腔种植学[M]. 第8版. 北京: 人民卫生出版社, 2020:1-6.
[2] Camps-Font O, Figueiredo R, Valmaseda-Castellón E, et al.Postoperative Infections After Dental Implant Placement: Prevalence, Clinical Features, and Treatment[J]. Implant Dent, 2015, 24(6):713-719.
[3] Kubde D, Badge AK, Ugemuge S, et al.Importance of Hospital Infection Control[J]. Cureus, 2023, 15(12):e50931.
[4] Esposito M, Hirsch JM, Lekholm U, et al.Biological factors contributing to failures of osseointegrated oral implants. (II). Etiopathogenesis[J]. Eur J Oral Sci, 1998, 106(3):721-764.
[5] Mosaddad SA, Talebi S, Keyhan SO, et al.Dental implant considerations in patients with systemic diseases: An updated comprehensive review[J]. J Oral Rehabil, 2024, 51(7):1250-1302.
[6] Naujokat H, Kunzendorf B, Wiltfang J.Dental implants and diabetes mellitus-a systematic review[J]. Int J Implant Dent, 2016, 2(1):5.
[7] Monje A, Catena A, Borgnakke WS.Association between diabetes mellitus/hyperglycaemia and peri-implant diseases: systematic review and Meta-analysis[J]. J Clin Periodontol, 2017, 44(6):636-648.
[8] Cappuccio FP, Meilahn E, Zmuda JM, et al.High blood pressure and bone-mineral loss in elderly white women: a prospective study. Study of Osteoporotic Fractures Research Group[J]. Lancet, 1999, 354(9183):971-975.
[9] Yang S, Nguyen ND, Eisman JA, et al.Association between beta-blockers and fracture risk: a Bayesian meta-analysis[J]. Bone, 2012, 51(5):969-974.
[10] Seymour R, Ellis J, Thomason J, et al.Amlodipine-induced gingival overgrowth[J]. J Clin Periodontol, 1994, 21(4):281-283.
[11] Duttenhoefer F, Fuessinger MA, Beckmann Y, et al.Dental implants in immunocompromised patients: a systematic review and meta-analysis[J]. Int J Implant Dent, 2019, 5(1):43.
[12] Huang M, Wang C, Li P, et al.Role of immune dysregulation in peri-implantitis[J]. Front Immunol, 2024, 15:1466417.
[13] Tabrizi R, Zarchini R, Ozkan BT, et al.Dental Implant Survival after Postoperative Infection[J]. J Maxillofac Oral Surg, 2022, 21(3):796-801.
[14] Siqueira MF, Li J, Chehab L, et al.Impaired wound healing in mouse models of diabetes is mediated by TNF-alpha dysregulation and associated with enhanced activation of forkhead box O1 (FOXO1)[J]. Diabetologia, 2010, 53(2):378-388.
[15] Wu YY, Xiao E, Graves DT.Diabetes mellitus related bone metabolism and periodontal disease[J]. Int J Oral Sci, 2015, 7(2):63-72.
[16] Alrabiah M, Al-Aali KA, Al-Sowygh ZH, et al.Association of advanced glycation end products with peri-implant inflammation in prediabetes and type 2 diabetes mellitus patients[J]. Clin Implant Dent Relat Res, 2018, 20(4):535-540.
[17] Wu X, Al-Abedalla K, Eimar H, et al.Antihypertensive medications and the survival rate of osseointegrated dental implants: a cohort study[J]. Clin Implant Dent Relat Res, 2016, 18(6):1171-1182.
[18] Neves J, de Araújo NM, Oliveira P, et al. Risk factors for implant failure and peri-implant pathology in systemic compromised patients[J]. J Prosthodont, 2018, 27(5):409-415.
[19] Ibañez C, Catena A, Galindo-Moreno P, et al.Relationship Between Long-Term Marginal Bone Loss and Bone Quality, Implant Width, and Surface[J]. Int J Oral Maxillofac Implants, 2016, 31(2):398-405.
[20] Figueiredo R, Camps-Font O, Valmaseda-Castellón E, et al.Risk Factors for Postoperative Infections After Dental Implant Placement: A Case-Control Study[J]. J Oral Maxillofac Surg, 2015, 73(12):2312-2318.
[21] Munakata M, Kataoka Y, Yamaguchi K, et al.Risk Factors for Early Implant Failure and Selection of Bone Grafting Materials for Various Bone Augmentation Procedures: A Narrative Review[J]. Bioengineering (Basel), 2024, 11(2):192.
[22] Belibasakis GN, Manoil D.Microbial Community-Driven Etiopathogenesis of Peri-Implantitis[J]. J Dent Res, 2021, 100(1):21-28.
[23] Schwarz F, Ramanauskaite A.It is all about peri-implant tissue health[J]. Periodontol 2000, 2022, 88:9-12.
[24] Kang DY, Kim M, Lee SJ, et al.Early implant failure: A retrospective analysis of contributing factors[J]. J Periodontal Implant Sci, 2019, 49:287-298.
[25] Jemt T.A retro-prospective effectiveness study on 3448 implant operations at one referral clinic: A multifactorial analysis. Part I: Clinical factors associated to early implant failures[J]. Clin Implant Dent Relat Res, 2017, 19:980-988.
[26] Carr AB, Arwani N, Lohse CM, et al.Early implant failure associated with patient factors, surgical manipulations, and systemic conditions[J]. J Prosthodont, 2019, 28:623-633.
[27] 杨杰. 口腔种植治疗的技术进展及并发症综述[J]. 国际口腔科学研究, 2024, 3(2):23-38.
[28] Garg AK, Reddi SN, Chacon GE.The importance of asepsis in dental implantology[J]. Implant Soc, 1994, 5(3):8-11.
[29] 徐慧玲, 梁怡青. 基于因果图分析法的口腔种植手术相关感染综合管理措施探讨[J]. 中国卫生标准管理, 2023, 14(14):165-169.
[30] Yu H, Zhou A, Liu J, et al.Management of systemic risk factors ahead of dental implant therapy: A beard well lathered is half shaved[J]. J Leukoc Biol, 2021, 110(3):591-604.
[31] Theadom A, Cropley M.Effects of preoperative smoking cessation on the incidence and risk of intraoperative and postoperative complications in adult smokers: a systematic review[J]. Tob Control, 2006, 15(5):352-358.
[32] Shigeishi H, Ohta K, Fujimoto S, et al.Preoperative oral health care reduces postoperative inflammation and complications in oral cancer patients[J]. Exp Ther Med, 2016, 12(3):1922-1928.
[33] Rotim Ž, Pelivan I, Sabol I, et al.THE EFFECT OF LOCAL AND SYSTEMIC FACTORS ON DENTAL IMPLANT FAILURE - ANALYSIS OF 670 PATIENTS WITH 1260 IMPLANTS[J]. Acta Clin Croat, 2022, 60(3):367-372.
[34] Torof E, Morrissey H, Ball PA.Antibiotic Use in Dental Implant Procedures: A Systematic Review and Meta-Analysis[J]. Medicina (Kaunas), 2023, 59(4):713.
[35] Chu B, Marwaha K, Sanvictores T, et al.Physiology, Stress Reaction[M]. In StatPearls. Treasure Island (FL): StatPearls Publishing; May 7, 2024.
[36] McHugh SM, Corrigan MA, Hill AD, et al. Surgical attire, practices and their perception in the prevention of surgical site infection[J]. Surgeon, 2014, 12(1):47-52.
[37] 张秀芳, 童兴旺. 口腔多学科联合修复对前牙缺损种植修复患者口腔功能及不良反应的影响[J]. 吉林医学, 2023, 44(11):3075-3078.
[38] 张方明. 口腔多学科协作诊疗体系的构建与实施[J]. 中华口腔医学杂志, 2020, 55(10):722-728.
[39] Myles PS, Iacono GA, Hunt JO, et al.Risk of respiratory complications and wound infection in patients undergoing ambulatory surgery: smokers versus nonsmokers[J]. Anesthesiology, 2002, 97(4):842-847.
[40] Bhatia AP, Rupamalini SN, Sathi KV, et al.Impact of the Habit of Alcohol Consumption on the Success of the Implants: A Retrospective Study[J]. J Pharm Bioallied Sci, 2024, 16(Suppl 1):S146-S148.
[41] Ata-Ali J, Ata-Ali F, Ata-Ali F.Do antibiotics decrease implant failure and postoperative infections? A systematic review and meta-analysis[J]. Int J Oral Maxillofac Surg, 2014, 43(1):68-74.
[42] Kashani H, Hilon J, Rasoul MH, et al.Influence of a single preoperative dose of antibiotics on the early implant failure rate. A randomized clinical trial[J]. Clin Implant Dent Relat Res, 2019, 21(2):278-283.
[43] 刘湘艳, 程晓卉, 谢小星, 等. 舒适护理结合健康教育对人工种植牙手术患者护理满意度与术后并发症发生率的影响[J]. 黔南民族医专学报, 2023, 36(2):122-124.
[44] Momand P, Becktor JP, Naimi-Akbar A, et al.Effect of antibiotic prophylaxis in dental implant surgery: A multicenter placebo-controlled double-blinded randomized clinical trial[J]. Clin Implant Dent Relat Res, 2022, 24(1):116-124.
[45] Esposito M, Cannizzaro G, Bozzoli P, et al.Effectiveness of prophylactic antibiotics at placement of dental implants: A pragmatic multicentre placebo-controlled randomised clinical trial[J]. Eur J Oral Implant, 2010, 3(2):135-143.
[46] Nolan R, Kemmoona M, Polyzois I, et al.The influence of prophylactic antibiotic administration on post-operative morbidity in dental implant surgery. A prospective double blind randomized controlled clinical trial[J]. Clin Oral Implant Res, 2013, 25(2):252-259.
[47] Toledano-Osorio M, Vallecillo C, Toledano R, et al.A Systematic Review and Meta-Analysis of Systemic Antibiotic Therapy in the Treatment of Peri-Implantitis[J]. Int J Environ Res Public Health, 2022, 19(11):6502.
[48] 周萍. 定期口腔健康宣教在牙周病患者种植术后护理中的效果评价[J]. 中华养生保健, 2023, 41(11):127-130.
[49] 中央政府门户网站. 医院感染管理办法[EB/OL]. 中华人民共和国卫生部令第48号. [2006-07-25]. 访问网址: http://www.gov.cn/ziliao/flfg/2006-07/25/content_344886.htm.
[50] Morton D, Wismeijer D, Chen S, et al. Group 5 ITI Consensus Report: Implant placement and loading protocols[J]. Clin Oral Implants Res, 2023, 34 Suppl 26:349-356.
[51] van Buijtene A, Foster D. Does a hospital culture influence adherence to infection prevention and control and rates of healthcare associated infection? A literature review[J]. J Infect Prev, 2019, 20(1):5-17.

口腔种植科诊疗中的感染控制

Infection Control in Oral Implantology

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

参考文献

相关文章 7

编辑推荐

Metrics

本文评价

[1]	吴补领, 高金, 刘伟. 根管治疗术中的感染控制[J]. 中国口腔医学继续教育杂志, 2025, 28(2): 61-66.
[2]	徐丹慧, 丁建芬, 林海燕, 胡凯, 辛子熙, 刘翠梅, 朱洪平. 口腔颌面外科住院患者的医院感染监测与控制[J]. 中国口腔医学继续教育杂志, 2025, 28(2): 76-82.
[3]	林芳汝, 朱文昊. 活髓保存治疗的感染控制策略[J]. 中国口腔医学继续教育杂志, 2025, 28(1): 3-6.
[4]	梁杰, 陈琳, 于甜甜, 张佳, 许胜, 张静, 柳忠豪. 分步教学法在数字化种植导板设计培训中的应用[J]. 中国口腔医学继续教育杂志, 2024, 27(2): 150-154.
[5]	朱凯茜, 林深, 陈思睿, 顾晨扬, 胡思嘉, 姜上洲, 张珊珊. 城市居民义齿修复方式临床决策偏好研究[J]. 中国口腔医学继续教育杂志, 2021, 24(1): 42-51.
[6]	曾维铭. 经过或未经过高压氧处理的种植体在放射线处理后的大鼠胫骨中骨整合现象的实验研究[J]. 中国口腔医学继续教育杂志, 2020, 23(3): 150-156.
[7]	许彬欣, 张新春. 口腔种植体的锐钛涂层表面抑制细菌定植的有效性：一项导向性体内实验[J]. 中国口腔医学继续教育杂志, 2020, 23(2): 114-121.