Abstract: Objective: This article reports a case of a patient with multiple oral diseases, including anterior tooth avulsion, multiple caries and missing teeth, who underwent a comprehensive dental treatment. Diagnosis and treatment: After comprehensive dental examination, the patient's diagnoses included anterior teeth trauma, caries, wedge-shaped defect, chronic pulpitis, residual roots, chronic periodontitis and dentition defect. After ruling out systemic injuries such as cranial trauma, emergency treatment was performed to control acute symptoms and address the anterior tooth injury, including replantation of the avulsed tooth and fixation of the lateral luxated tooth. During the disease prevention and control period, oral hygiene instruction was provided with plaque control as the core, periodontal treatment to control periodontal infection, root canal treatment to control pulp infection, filling treatment to control carious infection, and extraction treatment for hopeless residual roots and wisdom teeth without opposing arch tooth. During the functional and aesthetic restoration period, teeth undergone root canal treatment and missing teeth were repaired. Regular follow-ups and maintenance treatments were performed during the maintenance period. Results: During 5.5 years of maintenance and follow-up, the replanted tooth was removed due to external root resorption and root fracture in the 4th year and replaced with an implant. The patient had good caries control, and the effects of root canal treatment, periodontal treatment, and implant restoration were stable. Conclusions: For patients with multiple oral diseases, a comprehensive and scientific treatment plan should be developed in consultation with the patient based on a comprehensive examination and evaluation. Standardized treatment focusing on etiology analysis and prevention can simplify laterally avulsion oral disease problems and help achieve and maintain long-term oral health.

Key words: comprehensive dental treatment plan, anterior tooth trauma, tooth replantation, predisposing factors of caries, management of caries-prone individuals