Abstract: Objective: This case report describes a child with craniofacial developmental malformations and early childhood caries who was treated with oral comfort under general anesthesia. Diagnosis and treatment: After making a clear diagnosis and obtaining the informed consent of the family members, the patient's facial development abnormalities and airway conditions were thoroughly evaluated, general anesthesia induction was performed under full anesthesia preparation, unexpected situations occurred during intubation were timely handled, and the dental decay treatment, lipid adhesion repair, root canal treatment, preformed metalcrown placement, space retainer placement, and flouride treatment comfort oral treatment were successfully completed. Results: Fifteen teeth were treated in a single session, with a surgical duration of 100 minutes and anesthesia duration of 130 minutes. Follow-up phone calls were conducted at 24 and 48 hours after discharge, during which the patient reported no discomfort. The family of the patient expressed a high level of satisfaction with a visual analogue scale (VAS) score of 10. Conclusions: General anesthesia with ‘8-step anesthesia management’ as the core can assist children caries treatment to achieve the two goals of safety and comfort.

Key words: early childhood caries, general anesthesia, oral comfort treatment, child airway assessment, precision anesthesia management