Combined Neodymium-yttrium Aluminum Garnet Laser and Photodynamic Therapy for 3 Cases of Oral Leukoplakia with Hyperkeratosis

doi:10.12337/zgkqjxjyzz.2024.02.005

Chinese Journal of Stomatological Continuing Education ›› 2024, Vol. 27 ›› Issue (2): 144-149.DOI: 10.12337/zgkqjxjyzz.2024.02.005

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Combined Neodymium-yttrium Aluminum Garnet Laser and Photodynamic Therapy for 3 Cases of Oral Leukoplakia with Hyperkeratosis

Jinjin Zhao¹, Yang Cai^2,*

¹Department of Clinical Medicine, Bijie Medical College, Bijie, Guizhou Province, P.R. China;
²Department of Periodontics & Oral Medicine, Stomatological Hospital Affiliated to Guizhou Medical University, Guiyang, Guizhou Province, P.R. China

Online:2024-03-31 Published:2024-09-23
Contact: Yang Cai. Tel: 0851-88549478. Email: caiyang85@163.com. Address: No.9 Beijing Road, Yunyan District, Guiyang 550001, Guizhou Province, P.R. China.
Supported by:
Guangdong Tianjin Guizhou innovative talent team helps explore the path to improve the quality of vocational stomatological technology talent training-taking Bijie Medical College as an example (No. BJYZXK202322)

Abstract

Abstract: Objective: To observe the clinical efficacy of neodymium-yttrium aluminum garnet (Nd:YAG)laser combined with 5-aminolevulinic acid photodynamic therapy (ALA-PDT) in the treatment of patients with hyperkeratotic oral leukoplakia, in order to provide a reference for the clinical application of this therapy. Diagnosis and treatment: Three patients with hyperkeratotic oral leukoplakia with different abnormal hyperplasia were treated with Nd:YAG laser combined with ALA-PDT. The therapeutic effect was evaluated by comparing the lesion area before and after operation. Results: After combined treatment, the white lesions on the tongue belly of 3 patients disappeared completely. The patients were followed up for 24 months without recurrence. Conclusions: Nd:YAG laser combined with ALA-PDT can be used as a new treatment for oral leukoplakia (OLK) with hyperkeratosis.

Key words: oral leukoplakia, Nd:YAG laser, 5-aminolevulinic acid, therapy, photodynamic

Jinjin Zhao, Yang Cai. Combined Neodymium-yttrium Aluminum Garnet Laser and Photodynamic Therapy for 3 Cases of Oral Leukoplakia with Hyperkeratosis[J]. Chinese Journal of Stomatological Continuing Education, 2024, 27(2): 144-149.

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Combined Neodymium-yttrium Aluminum Garnet Laser and Photodynamic Therapy for 3 Cases of Oral Leukoplakia with Hyperkeratosis

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